After the disappearance of some of their close friends on their 21st birthday, overly determined Isa/Isaac is left to pick up the pieces of the tragedy, fueled by their misdirected motivation. Years later, lost, misguided, and frustrated, Isa/Isaac is about to call it quits. But not before the lead, they've been looking for comes knocking at her door. "I-21" is intended to have dual casting and two movie versions released, highlighting how targets of human trafficking are not isolated to one gender.