In the remote region of Rhode, all Pokemon have long since disappeared. The days of monsters leaping from tall grass seem to be over, and only a few Cacturnes can be seen here and there, letting themselves be pecked by the rare desert scavengers. In the ruins of Pyrite, the last inhabitants try to survive in the heart of this forgotten world, until the day they discover a baby Kangaskhan. Convinced that this creature holds the secret behind the Pokemon's disappearance, Mike, the group's scientist, promises to do everything to find his family...